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CAS 86-74-8

Carbazole

CarcinogenVOC

Carbazole is a nitrogen-containing chemical found in coal tar and used to make dyes and pigments. It can be released during coal processing and related industries, so it may show up in air, dust, soil, and certain products [1][2].

Where It Comes From

Byproduct of coal tar/creosote and petroleum refining; manufactured as an intermediate for dyes, pigments, and some plastics/pharmaceuticals [1][2].

How You Are Exposed

Breathing workplace air during coal‑tar distillation, creosote wood treatment, or pigment manufacture; skin contact with coal‑tar products; contact with contaminated soil/dust near old gasworks, coking plants, or treated‑wood sites [1][3].

Why It Matters

Can irritate eyes and skin; high‑dose animal studies report liver effects. IARC has not classified carbazole as carcinogenic to humans (Group 3) [4][5].

Who Is at Risk

Workers handling coal tar/creosote or making dyes/pigments; people living near contaminated industrial or Superfund sites; children who ingest dust from floors or soil [1][3].

How to Lower Your Exposure

Choose tar‑free/asphalt‑based sealants; avoid skin contact with coal‑tar products; reduce indoor dust (wet mopping, HEPA vacuum); wash hands often; at work, use ventilation, gloves, and follow safety guidance [1][3][6].

References

  1. [1]ATSDR. Toxicological Profile for Coal Tar and Coal-Tar Pitch. U.S. DHHS. https://www.atsdr.cdc.gov/toxprofiles/tp33.pdf
  2. [2]U.S. EPA. CompTox Chemicals Dashboard: Carbazole (CASRN 86-74-8). https://comptox.epa.gov/dashboard/chemical/details/DTXSID4020667
  3. [3]ATSDR. ToxFAQs for Creosote. https://www.atsdr.cdc.gov/toxfaqs/tf.asp?id=63&tid=18
  4. [4]U.S. EPA. Provisional Peer-Reviewed Toxicity Values (PPRTV) for Carbazole (CASRN 86-74-8).
  5. [5]IARC. Agents Classified by the IARC Monographs—Carbazole (Group 3). https://monographs.iarc.who.int/agents-classified-by-the-iarc/
  6. [6]NJ Dept. of Health. Hazardous Substance Fact Sheet: Carbazole. https://www.nj.gov/health/eoh/rtkweb/documents/fs/0339.pdf

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