Where It Comes From
Occurs with strychnine in Strychnos nux-vomica/ignatii seeds; used in research and chemical analysis [2][3].
How You Are Exposed
Ingesting Strychnos seeds or herbal remedies made from them; accidental/intentional poisoning; lab handling without protection [1][2][3].
Why It Matters
Like strychnine, it blocks glycine receptors, causing rigidity, painful convulsions, and breathing failure; symptoms can start within minutes to hours—seek emergency care [1][2].
Who Is at Risk
People using traditional remedies containing Strychnos extracts; children and pets with access to seeds/products; laboratory workers [1][2][3].
How to Lower Your Exposure
Avoid products listing nux-vomica/Strychnos; choose third‑party tested supplements; lock away toxic plant materials; use PPE and hoods in labs; if exposure is suspected, call Poison Help (1‑800‑222‑1222) [2][4].
References
- [1]ATSDR. ToxFAQs: Strychnine. https://wwwn.cdc.gov/TSP/ToxFAQs/ToxFAQsDetails.aspx?faqid=707&toxid=122
- [2]WHO IPCS. Poisons Information Monograph: Strychnine (PIM 521). https://inchem.org/documents/pims/chemical/pim521.htm
- [3]PubChem. Brucine Compound Summary (CID 6098). https://pubchem.ncbi.nlm.nih.gov/compound/Brucine
- [4]CDC. Poisoning Prevention and Control. https://www.cdc.gov/poisoning/