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CAS 108-60-1

Bis(2-chloro-1-methylethyl) ether

Bis(2-chloro-1-methylethyl) ether (also called bis(2-chloroisopropyl) ether, BCIPE) is a manufactured chlorinated ether used mainly to make other chemicals. Although use has declined, it can still contaminate air and water near industrial facilities and hazardous waste sites. [1][2]

Where It Comes From

Released during chemical production/use, spills, and disposal; found at some hazardous waste sites and nearby air or water. [1][2]

How You Are Exposed

Breathing workplace air; drinking or showering with contaminated water; skin contact with contaminated liquids or soils near waste areas. [1][2]

Why It Matters

Can irritate eyes, nose, and lungs; longer exposure may harm the liver and kidneys. Animal studies show tumors; IARC says it’s possibly carcinogenic (Group 2B), and EPA considers it a possible human carcinogen. [1][2][3]

Who Is at Risk

Chemical plant and waste-site workers; people living near contaminated sites or using nearby private wells; infants, children, and pregnant people may be more vulnerable. [1][2]

How to Lower Your Exposure

Use workplace protections; test private wells; consider certified carbon or reverse osmosis filters for VOCs; ventilate when showering if water is impacted; follow local cleanup advisories. [1][2][4]

References

  1. [1]ATSDR. ToxFAQs for Chloroethers (BCEE and BCIPE). Agency for Toxic Substances and Disease Registry.
  2. [2]U.S. EPA. IRIS: Bis(2-chloroisopropyl) ether (CASRN 108-60-1).
  3. [3]IARC. Monographs: Bis(2-chloroisopropyl) ether – Group 2B (possibly carcinogenic).
  4. [4]CDC/NIOSH. Pocket Guide to Chemical Hazards: Bis(2-chloroisopropyl) ether.

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