Where It Comes From
Made industrially; released during manufacturing and product use; present in tobacco smoke; can form in air from other aromatics like ethylbenzene; occurs naturally in some foods. [1][2]
How You Are Exposed
Breathing indoor/outdoor air (especially near facilities or when using fragranced products), workplace air, skin contact with products; drinking water is a less common source. [1][2][3]
Why It Matters
Short-term exposure can cause eye/skin irritation, headache, dizziness, and sleepiness; very high levels may lead to unconsciousness. Repeated high exposures caused liver and kidney effects in animals; evidence for cancer in humans is inadequate. [1][2]
Who Is at Risk
Workers in fragrance, resin, or chemical plants; people who smoke or are around smoke; anyone using many scented products in small or poorly ventilated spaces; people with asthma or chemical sensitivities. [1][2][3]
How to Lower Your Exposure
Choose fragrance-free products, ventilate when using scented or solvent-containing items, avoid tobacco smoke, and follow workplace ventilation/PPE guidance. Store chemicals tightly closed. [1][3]
References
- [1]ATSDR. ToxFAQs for Acetophenone (CAS 98-86-2). Agency for Toxic Substances and Disease Registry.
- [2]U.S. EPA. Acetophenone Hazard Summary (Technology Transfer Network Air Toxics).
- [3]NIOSH. Pocket Guide to Chemical Hazards: Acetophenone. Centers for Disease Control and Prevention.