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CAS 194-59-2

7H-Dibenzo[c,g]carbazole

7H-Dibenzo[c,g]carbazole (DBC) is a nitrogen‑containing polycyclic aromatic compound formed when coal, oil, tobacco, or wood are burned. It causes cancer in laboratory animals and is evaluated by health agencies because of these hazards [1][3].

Where It Comes From

By‑product of incomplete combustion; found in cigarette smoke, coal‑tar pitch, diesel exhaust, and urban air [1][2].

How You Are Exposed

Breathing smoke or exhaust, secondhand smoke, eating heavily charred or smoked foods, or skin contact with soot/coal‑tar products (e.g., some roofing or paving materials) [2][4].

Why It Matters

DBC binds to DNA and can cause mutations and tumors in animals; it contributes to the overall cancer risk from PAH mixtures in polluted air [1][3].

Who Is at Risk

Smokers and their households; workers around coke ovens, aluminum production, asphalt/coal‑tar, or diesel equipment; people living near heavy traffic or industrial sites [2][4].

How to Lower Your Exposure

Don’t smoke and avoid secondhand smoke; ventilate while cooking and avoid charring foods; limit time near idling engines; follow workplace controls, PPE, and hygiene when handling coal‑tar or sooty materials [2][4].

References

  1. [1]IARC Monographs on the Evaluation of Carcinogenic Risks to Humans: 7H‑Dibenzo[c,g]carbazole.
  2. [2]ATSDR. Toxicological Profile for Polycyclic Aromatic Hydrocarbons (PAHs).
  3. [3]NTP. Bioassay/Technical Report on 7H‑Dibenzo[c,g]carbazole (CAS 194‑59‑2) carcinogenicity.
  4. [4]U.S. EPA. Polycyclic Aromatic Hydrocarbons (PAHs): Sources, exposure, and health effects.

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