Where It Comes From
Manufacture/use of AFFF firefighting foams, chrome-plating mist suppressants, and stain-/water-repellent treatments; in water it dissociates to PFHxS [1].
How You Are Exposed
Drinking contaminated water near airports, military sites, plating shops, or PFAS facilities; eating food or dust with PFAS; workplace contact via air/skin [1][3].
Why It Matters
PFHxS has a long human half-life (~8 years) and studies associate exposure with higher cholesterol, liver enzyme changes, reduced vaccine response, and thyroid/developmental effects [1][3].
Who Is at Risk
Residents with PFAS-contaminated water; firefighters and plating/PFAS-industry workers; pregnant people, fetuses, and infants (PFHxS crosses the placenta and is found in breast milk) [1][3].
How to Lower Your Exposure
Use alternative water or NSF-certified PFAS filters (activated carbon or reverse osmosis), follow local advisories, reduce indoor dust (wet-wiping, HEPA vacuum), choose PFAS-free products when possible, and use workplace PPE/hygiene. Breastfeeding has many benefits; discuss concerns with your clinician [1][2][3].
References
- [1]ATSDR. Toxicological Profile for Perfluoroalkyls (PFAS). 2021. https://www.atsdr.cdc.gov/toxprofiles/tp200.pdf
- [2]U.S. EPA. Home Water Treatment Units That May Reduce PFAS in Drinking Water. 2022. https://www.epa.gov/system/files/documents/2022-06/drinking-water-adv-fact-sheet-pfas-home-water-treatment.pdf
- [3]CDC. Biomonitoring Summary: Perfluorohexane Sulfonic Acid (PFHxS). https://www.cdc.gov/biomonitoring/PFHxS_BiomonitoringSummary.html