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CAS 68758-57-6

1-Tetradecanesulfonyl chloride, 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12,13,13,14,14,14-pentacosafluoro-

This is a long-chain PFAS precursor used to make fluorinated surfactants and water- and oil-repellent coatings. It matters because it can form very persistent perfluoroalkyl sulfonic acids and contribute to PFAS pollution in people and the environment [1][2].

Where It Comes From

Industrial production of fluorinated treatments for textiles, paper, metal plating, and specialty surfactants; breakdown/processing to long-chain perfluoroalkyl sulfonic acids (e.g., C14 PFSA) [1][2].

How You Are Exposed

Workplace inhalation or skin contact; contaminated drinking water near PFAS production or firefighting foam sites; indoor dust from treated goods; eating contaminated fish or game [1][2].

Why It Matters

Long-chain PFAS are extremely persistent, can build up in people and wildlife, and are linked to immune effects, higher cholesterol, liver and developmental effects; some (like PFOA) cause cancer in humans [1][3][4].

Who Is at Risk

Workers handling PFAS or sulfonyl chlorides; people near PFAS facilities, airports, or bases; pregnant people and infants; private well users; those who eat a lot of locally caught fish [1][2][3].

How to Lower Your Exposure

Check local PFAS water results; use certified home filters that reduce PFAS (reverse osmosis, activated carbon, ion exchange); follow fish advisories; choose PFAS-free products when possible; follow workplace PPE and hygiene [5][6].

References

  1. [1]ATSDR. Toxicological Profile for Perfluoroalkyls (2021).
  2. [2]U.S. EPA. Our Current Understanding of the Human Health and Environmental Risks of PFAS. https://www.epa.gov/pfas
  3. [3]NTP. Immunotoxicity Associated with Exposure to PFOA and PFOS (2016).
  4. [4]IARC. PFOA carcinogenic to humans; PFOS possibly carcinogenic (Monographs Vol 135, 2023).
  5. [5]CDC/ATSDR. PFAS and Your Health. https://www.atsdr.cdc.gov/pfas/
  6. [6]U.S. EPA. Reducing PFAS in Your Drinking Water at Home. https://www.epa.gov/pfas/reducing-pfas-drinking-water-home

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