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CAS 68555-75-9

1-Hexanesulfonamide, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-N-(2- hydroxyethyl)-N-methyl-

This fluorinated surfactant (a PFAS) is used in stain- and water-repellent coatings and industrial processes. It can transform into persistent PFAS such as perfluorohexane sulfonate (PFHxS) and can build up in people and the environment [1][2].

Where It Comes From

PFAS-treated textiles and papers, industrial coatings, and some firefighting foams; releases from manufacturing, use, and waste/cleanup sites [1][2].

How You Are Exposed

Drinking water near contaminated facilities or fire-training areas; indoor dust; contact with treated products; some foods (fish, game) [1][3].

Why It Matters

Very persistent; accumulates in blood. Studies of PFHxS and related PFAS link exposure with higher cholesterol, reduced vaccine response, thyroid changes, and developmental effects; EPA now regulates several PFAS in drinking water [1][2].

Who Is at Risk

People with PFAS-impacted water, workers using AFFF or PFAS coatings, pregnant people, infants, and children [1][3].

How to Lower Your Exposure

Follow local water advisories; consider alternative water or filters certified to reduce PFAS; heed fish/foam advisories; wet-dust/HEPA vacuum; choose products without stain-repellent PFAS [1][2][3].

References

  1. [1]ATSDR. Toxicological Profile for Perfluoroalkyls (PFAS). 2021. https://www.atsdr.cdc.gov/toxprofiles/tp200.pdf
  2. [2]U.S. EPA. Final National Primary Drinking Water Regulation for PFAS. 2024. https://www.epa.gov/sdwa/epas-pfas-npdwr
  3. [3]CDC/ATSDR. PFAS and Your Health. https://www.atsdr.cdc.gov/pfas/index.html

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