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CAS 68187-25-7

Butanoic acid, 4-[[3-(dimethylamino)propyl]amino]-4-oxo-, 2(or 3)-[(γ-ω-perfluoro-C6-20-alkyl)thio] derivs.

This substance is a fluorinated surfactant in the PFAS family. It’s used to make materials resist water, oil, and stains, and has been used in some firefighting foams. PFAS matter because they persist for years and can build up in people and the environment [1][2].

Where It Comes From

Made and used for stain-, water-, and grease-resistant treatments on textiles, paper, and industrial goods; some AFFF firefighting foams. Considered part of EPA’s long‑chain PFAS group (C6–C20) [2].

How You Are Exposed

Drinking contaminated water (near plants, airports, landfills), eating fish/wildlife from affected waters, contact with treated products, or workplace use in PFAS manufacturing, metal plating, and firefighting [1][2].

Why It Matters

PFAS exposure is linked to reduced vaccine response, higher cholesterol, liver effects, and lower infant birth weight; some PFAS (like PFOA) cause cancer in humans [1][3][4].

Who Is at Risk

Workers handling PFAS or AFFF; communities near PFAS facilities or training sites; pregnant people, infants, and children [1][2].

How to Lower Your Exposure

Check local water advisories; use certified activated carbon or reverse osmosis filters; follow fish advisories; choose PFAS‑free stain/water‑resistant products; limit AFFF use and follow safety guidance [1][2].

References

  1. [1]ATSDR. Toxicological Profile for Perfluoroalkyls (Per- and Polyfluoroalkyl Substances). Agency for Toxic Substances and Disease Registry, 2021.
  2. [2]U.S. EPA. PFAS Explained; Reducing PFAS in Drinking Water; Long‑Chain PFAS (LCPFAC) Significant New Use Rule. U.S. Environmental Protection Agency, 2020–2024.
  3. [3]NTP. Monograph on Immunotoxicity Associated with Exposure to Perfluorooctanoic Acid (PFOA) and Perfluorooctane Sulfonate (PFOS). National Toxicology Program, 2016.
  4. [4]IARC. Perfluorooctanoic acid (PFOA). IARC Monographs, Volume 135, 2023.

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