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CAS 92-93-3

4-Nitrobiphenyl

4-Nitrobiphenyl is a man‑made chemical used to make dyes and rubber chemicals. It is toxic, can be absorbed through the skin or inhaled, and long-term exposure may increase cancer risk [1][2].

Where It Comes From

Made as an intermediate for dye and rubber production; also used in research. Can be found at older industrial sites and in waste streams from these processes [1][2].

How You Are Exposed

Mostly at work—breathing contaminated air, skin contact with powders or solutions, or touching contaminated surfaces. Community exposure is uncommon but can occur near facilities or spills [2].

Why It Matters

Can cause headaches, dizziness, nausea, and blue-tinged skin from methemoglobinemia; may damage liver and blood. Classified by IARC as possibly carcinogenic to humans (Group 2B) [1][2].

Who Is at Risk

Workers in dye, rubber, and specialty chemical production; maintenance and cleanup crews; laboratory staff; people living near poorly controlled facilities [2].

How to Lower Your Exposure

Use closed systems, local exhaust, and chemical-resistant gloves and clothing; avoid skin contact; wash up after work; follow NIOSH/OSHA controls. Near sites, test private wells and follow local advisories [2].

References

  1. [1]International Agency for Research on Cancer (IARC). IARC Monographs: 4-Nitrobiphenyl (Group 2B).
  2. [2]CDC/NIOSH. Pocket Guide to Chemical Hazards: p-Nitrobiphenyl (CAS 92-93-3).

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