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CAS 92-67-1

4-Aminobiphenyl

CarcinogenMutagen

4-Aminobiphenyl (4-ABP) is a toxic, man-made aromatic amine that causes cancer. Once used to make dyes and rubber chemicals, it is now tightly controlled; for most people, tobacco smoke is the main source [1][2].

Where It Comes From

Past use in dye/rubber-chemical manufacture; present in tobacco smoke; possible industrial emissions [1][2].

How You Are Exposed

Breathing cigarette smoke or secondhand smoke; workplace inhalation or skin contact in facilities handling aromatic amines, dyes, or rubber chemicals [1][2].

Why It Matters

Known human carcinogen (IARC Group 1; NTP). Strongly linked to urinary bladder cancer; risk increases with cumulative exposure [1][2].

Who Is at Risk

Smokers; people exposed to secondhand smoke at home, in cars, or in indoor public places; workers in dye/rubber/chemical manufacturing or labs [1][2].

How to Lower Your Exposure

Don’t smoke and avoid secondhand smoke; make homes and cars smoke-free [3]. At work, use closed systems, ventilation, gloves, and protective clothing; follow exposure monitoring and hygiene practices [1][2].

References

  1. [1]IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Volume 100F: Chemical Agents and Related Occupations. 4-Aminobiphenyl (Group 1). World Health Organization, 2012. https://publications.iarc.fr/
  2. [2]U.S. NTP, Report on Carcinogens, 15th ed. 4-Aminobiphenyl—Known to be a human carcinogen. https://ntp.niehs.nih.gov/whatwestudy/assessments/roc
  3. [3]CDC. Health Effects of Secondhand Smoke; there is no risk-free level of exposure. https://www.cdc.gov/tobacco/secondhand-smoke/health.html

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