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CAS 60-09-3

4-Aminoazobenzene

4-Aminoazobenzene is a synthetic “azo” dye ingredient used in making dyes and pigments and as a lab reagent. It is toxic and linked to cancer; IARC classifies it as possibly carcinogenic to humans, and NTP lists it as reasonably anticipated to be a human carcinogen [1][2].

Where It Comes From

Made for azo dye/pigment production and research; may be found in some strongly dyed materials from legacy or non‑compliant sources [1].

How You Are Exposed

Mostly at work by skin contact or breathing dust/vapors during manufacture, handling, or dyeing; the public could have skin contact with dyed textiles/leather if present [1][3].

Why It Matters

Causes liver tumors in animals; cancer concern for people. Can irritate skin/eyes and is absorbed through skin [1][2][3].

Who Is at Risk

Workers in dye/pigment manufacturing, laboratories, and textile/leather processing; people frequently handling the pure chemical or contaminated materials [1][3].

How to Lower Your Exposure

At work, use gloves, protective clothing, and local exhaust ventilation; avoid skin contact and follow hygiene practices. As a consumer, check product information, wash new dyed items before use, and limit prolonged skin contact with strongly dyed materials if concerned [3].

References

  1. [1]IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. Some Aromatic Azo Compounds. IARC; classification of 4‑aminoazobenzene (Group 2B).
  2. [2]National Toxicology Program (NTP). Report on Carcinogens, 15th ed. p‑Aminoazobenzene—Reasonably Anticipated to be a Human Carcinogen.
  3. [3]CDC/NIOSH. Pocket Guide to Chemical Hazards: p‑Aminoazobenzene (CAS 60‑09‑3). Exposure routes, hazards, and controls.

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