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CAS 1652-63-7

3-[[(Heptadecafluorooctyl)sulfonyl]amino]-N,N,N-trimethyl-1-propanaminium iodide

This substance is a PFAS-based surfactant and a PFOS-related compound. It matters because PFOS-related chemicals can transform into PFOS, a highly persistent pollutant linked to health harms and long-lasting environmental contamination [1][2].

Where It Comes From

Industrial uses of specialty surfactants and surface treatments (e.g., water/oil repellents), metal plating, and older firefighting foams; PFOS-related substances can degrade to PFOS in the environment [1][2].

How You Are Exposed

Drinking water near industrial sites, airports, or bases; household dust; some treated consumer goods; and workplace air or skin contact in affected industries [1][2].

Why It Matters

PFOS and related PFAS persist and bioaccumulate; associated with decreased vaccine antibody response, increased cholesterol, developmental effects, and liver/thyroid changes [1][3].

Who Is at Risk

Workers in fluorochemical manufacturing, metal plating, and firefighting; communities near contaminated sites; pregnant people, fetuses, and infants (transfer via placenta and breast milk) [1][3].

How to Lower Your Exposure

Check local PFAS water advisories; use NSF/ANSI 53 or 58 certified filters (activated carbon or reverse osmosis); limit “stain/water-resistant” products; follow workplace protections and hygiene [1][4].

References

  1. [1]ATSDR. Toxicological Profile for Perfluoroalkyls (PFAS). 2021.
  2. [2]EPA. Significant New Use Rules for PFOS and PFOS-related substances (40 CFR 721.9582) and PFOS basic information.
  3. [3]NTP. Monograph on Immunotoxicity Associated with PFOA and PFOS. 2016.
  4. [4]EPA. Reducing PFAS in Drinking Water with Home Treatment Devices (EPA 815-F-22-003). 2022.

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