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CAS 542-76-7

3-Chloropropionitrile

3-Chloropropionitrile is a toxic industrial chemical mainly used to make other chemicals, including pharmaceuticals and pesticides. It’s a liquid with a sharp, irritating odor that can harm skin, eyes, and lungs even at low levels [1][2].

Where It Comes From

Manufactured as a chemical intermediate for pharma, agrochemicals, and lab synthesis [2][3].

How You Are Exposed

Breathing vapors where it’s made or used, and through skin or eye contact during handling or spills; the general public is mainly at risk during industrial releases [1][2].

Why It Matters

Toxic if inhaled, swallowed, or absorbed through skin; causes severe skin and eye burns and can irritate the respiratory tract. High exposures may lead to serious nervous system effects and breathing problems [1][2][4].

Who Is at Risk

Workers in chemical manufacturing or synthesis labs, transport and waste handlers, and emergency responders; people near accidental releases [1][4].

How to Lower Your Exposure

At work, use closed systems and local exhaust; wear chemical-resistant gloves, goggles/face shield, and appropriate respirators; wash promptly after contact and follow spill-response plans. In the community, follow local health advisories and avoid areas during industrial incidents [1][4].

References

  1. [1]CDC/NIOSH Pocket Guide to Chemical Hazards: 3-Chloropropionitrile.
  2. [2]PubChem Compound Summary: 3-Chloropropionitrile (NIH/NLM).
  3. [3]EPA CompTox Chemicals Dashboard: 3-Chloropropionitrile.
  4. [4]New Jersey Department of Health, Hazardous Substance Fact Sheet: 3-Chloropropionitrile.

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