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CAS 27619-91-6

1-Dodecanesulfonyl chloride, 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12,12-heneicosafluoro-

A PFAS-related industrial chemical used to make oil- and water-repellent coatings. It matters because PFAS persist, build up in people, and some cause health harms [1][2].

Where It Comes From

Made for fluorinated coatings/surfactants; releases during manufacturing, use, or disposal; related compounds can turn into long‑lived perfluoroalkyl sulfonic acids [1][2].

How You Are Exposed

Workers by inhalation/skin; public mainly via contaminated water, indoor dust, and treated products, especially near PFAS sites [1][2][3].

Why It Matters

PFAS exposure is linked to higher cholesterol, reduced vaccine response, liver effects, pregnancy hypertension, lower birth weight; some PFAS (e.g., PFOA) are linked to cancers [1][3][4].

Who Is at Risk

Fluorochemical workers; people on private wells near plants or foam-release sites; pregnant people and infants [1][3].

How to Lower Your Exposure

Test private wells; use certified PFAS filters (activated carbon or reverse osmosis); avoid stain-/water-repellent products with “fluoro-/PFAS”; clean dust with HEPA/damp methods; follow workplace controls/PPE [2][3][5].

References

  1. [1]ATSDR. Toxicological Profile for Perfluoroalkyls (PFAS), 2021. https://www.atsdr.cdc.gov/toxprofiles/tp200.pdf
  2. [2]U.S. EPA. PFAS Explained. https://www.epa.gov/pfas/pfas-explained
  3. [3]CDC/ATSDR. PFAS and Your Health. https://www.atsdr.cdc.gov/pfas/index.html
  4. [4]IARC. Evaluation of PFOA and PFOS (Monographs Vol. 134), 2023. https://www.iarc.who.int/news-events/iarc-monographs-evaluate-pfoa-and-pfos-2023/
  5. [5]U.S. EPA. Technical Fact Sheet – PFAS (treatment options), 2021. https://www.epa.gov/system/files/documents/2021-12/technical-fact-sheet-pfas__december-2021_508.pdf

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