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CAS 90-43-7

2-Phenylphenol

Potential EDCPesticidesCarcinogen

2-Phenylphenol (o-phenylphenol, OPP) is an antimicrobial used to prevent mold on stored citrus fruit and as an ingredient in some disinfectant cleaners. It matters because it can irritate eyes, skin, and airways; high doses harmed the bladder and kidneys in animal studies [1][2].

Where It Comes From

Fungicide/preservative for citrus and other produce; ingredient in household/industrial disinfectants; also used as its sodium salt [1][3].

How You Are Exposed

Breathing or touching disinfectant sprays/wipes; handling treated fruit or working in packinghouses; small amounts on peels; occupational use in cleaning or manufacturing [1][3][4].

Why It Matters

Short-term irritation of skin, eyes, nose, and throat; stomach upset if swallowed; not classifiable for cancer in humans, though some animal studies found bladder tumors at high doses linked to urinary tract irritation [1][2][3].

Who Is at Risk

Fruit-packing and disinfection workers; frequent users of spray disinfectants; people with asthma or skin conditions; young children via hand-to-mouth contact [1][4].

How to Lower Your Exposure

Ventilate when cleaning; prefer wipes over sprays; wear gloves; follow labels; store chemicals safely; wash hands; rinse or peel citrus before eating [1][3].

References

  1. [1]ATSDR. ToxFAQs for o-Phenylphenol (OPP).
  2. [2]IARC Monographs, Vol. 73: o-Phenylphenol and Sodium o-phenylphenate.
  3. [3]U.S. EPA. Reregistration Eligibility Decision (RED) for o-Phenylphenol.
  4. [4]CDC/NIOSH Pocket Guide to Chemical Hazards: o-Phenylphenol.

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