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CAS 88-75-5

2-Nitrophenol (o-Nitrophenol)

2-Nitrophenol is a toxic industrial chemical mainly used to make dyes and other chemicals. It can also form in city air from reactions of other pollutants, so people may encounter small amounts in air, water, or near industrial sites [1].

Where It Comes From

Made as a chemical intermediate (dyes, rubber chemicals, pharmaceuticals); released from manufacturing and waste sites; also formed in the atmosphere and found in urban air and rain [1].

How You Are Exposed

Breathing workplace or urban air; skin contact or inhalation at work; drinking contaminated water; contact with contaminated soil or dust near waste sites [1].

Why It Matters

Irritates eyes and skin; high exposure can cause headache, nausea, and methemoglobinemia (reduces blood oxygen delivery) and may harm liver and kidneys; cancer data are inadequate [1][2].

Who Is at Risk

Workers who make or use it; people near industrial discharges or hazardous waste; children and people with heart, lung, or blood conditions (more sensitive to low oxygen) [1].

How to Lower Your Exposure

Follow workplace protections (ventilation, gloves, eye protection); check local air and water reports; avoid contact with water/soil near industrial outfalls; use indoor air filtration during smog episodes [1].

References

  1. [1]ATSDR. Toxicological Profile for Nitrophenols (2-Nitrophenol and 4-Nitrophenol). U.S. DHHS/CDC, 1992; Update 2000.
  2. [2]U.S. EPA. Integrated Risk Information System (IRIS): 2-Nitrophenol (CASRN 88-75-5). EPA.

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