← All chemicals

CAS 75-86-5

2-Methyllactonitrile (Acetone cyanohydrin)

Acetone cyanohydrin is a highly toxic industrial chemical used mostly to make acrylic plastics (methyl methacrylate). It can rapidly release hydrogen cyanide, a fast-acting poison, especially with heat, moisture, or acids [1][2].

Where It Comes From

Produced in chemical plants as an intermediate for methyl methacrylate and related resins/plastics [1].

How You Are Exposed

Mainly at work by breathing vapors or through skin/eye contact during production, transfer, or spills; nearby communities may be exposed during accidental releases [1][2].

Why It Matters

Extremely poisonous; converts to cyanide in the body, causing headache, dizziness, confusion, rapid breathing, seizures, cardiac arrest, and death at high doses; also corrosive to skin and eyes [1][2].

Who Is at Risk

Workers in methyl methacrylate/acetone cyanohydrin manufacturing, transport, or storage; emergency responders; people near industrial sites during accidents. Pregnant people, infants, and those with heart/lung disease may be more vulnerable to cyanide’s oxygen-blocking effects [2].

How to Lower Your Exposure

At work, use closed systems, local exhaust, monitoring, and chemical-resistant PPE; have cyanide emergency plans and trained responders [1][2]. In the community, follow official alerts, shelter-in-place or evacuate as directed, and avoid unknown spills/odors near facilities [2].

References

  1. [1]CDC/NIOSH Pocket Guide to Chemical Hazards: Acetone cyanohydrin (CAS 75-86-5).
  2. [2]ATSDR ToxFAQs and Toxicological Profile for Cyanide.

Track your exposure to 2-Methyllactonitrile (Acetone cyanohydrin)

Pollution Profile maps your lifetime exposure history to EPA-tracked chemicals.

Get early access

We use cookies and analytics to understand how people use Pollution Profile and improve the experience. We never sell your data. Learn more.