2-Methoxyethanol

Industrial solvents for paints/varnishes, cleaners, inks, electronics, and some aviation fluids; releases can occur during production and use [1][3].

Breathing vapors at work, skin contact with liquids or contaminated materials, and indoor air during/after using solvent-based products; highest exposures are occupational [1][2][3].

Short-term exposure can cause irritation, headache, and nausea; repeated or higher exposure can lower blood counts and damage the reproductive system. EGME’s metabolite (methoxyacetic acid) is a key cause of developmental and reproductive toxicity [1][2][4].

Workers in semiconductor/electronics, painting/coating, printing, and aircraft maintenance; people who are pregnant or trying to conceive; fetuses; anyone with significant skin contact due to strong skin absorption [1][2][3].

At work, substitute safer solvents, use closed systems/local exhaust, avoid skin contact, and use appropriate PPE per safety data sheets and NIOSH guidance; follow good hygiene. At home, choose products without 2‑methoxyethanol/EGME, ventilate well, and store/dispose safely [2][3].