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CAS 376-14-7

2-[Ethyl[(heptadecafluorooctyl)sulfonyl]amino]ethyl methacrylate

This is a PFAS-based building block used to make stain-, oil-, and water‑repellent coatings. It matters because PFAS are “forever chemicals” that persist, can travel long distances, and some can break down into PFOS, a harmful PFAS found in people and the environment [1][2].

Where It Comes From

Made for fluorinated coatings on textiles, leather, paper, and paints; released during manufacturing, product use, and disposal. Some related sulfonamide PFAS can transform to PFOS in the environment [1][2].

How You Are Exposed

Indoor dust from treated carpets/upholstery, use of waterproofing sprays, contaminated drinking water near facilities or landfills, eating contaminated fish, and on-the-job contact in fluorochemical work [1][2].

Why It Matters

PFAS can build up in people; exposure is linked to higher cholesterol, reduced vaccine response, liver and thyroid changes, and pregnancy/developmental effects. Some PFAS (PFOA) cause cancer; PFOS is possibly carcinogenic [1][2][3].

Who Is at Risk

Workers making/using fluorinated coatings; communities near production or contaminated water; pregnant people, infants, and those who eat a lot of locally caught fish where advisories exist [1][2].

How to Lower Your Exposure

Check local water reports; use certified filters (activated carbon, ion exchange, or reverse osmosis) for PFAS; choose PFAS‑free products; skip stain‑repellent treatments; wet‑dust/HEPA‑vacuum; follow fish advisories [1][2][4].

References

  1. [1]ATSDR. Toxicological Profile for Perfluoroalkyls (PFAS). U.S. DHHS, 2021.
  2. [2]U.S. EPA. Basic Information on PFAS. https://www.epa.gov/pfas
  3. [3]IARC Monographs (2023): PFOA carcinogenic to humans (Group 1); PFOS possibly carcinogenic (Group 2B).
  4. [4]U.S. EPA. Drinking Water Treatment for PFAS (GAC, RO, ion exchange). https://www.epa.gov/pfas/drinking-water-treatment-pfas

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