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CAS 87-62-7

2,6-Xylidine

PesticidesCarcinogen

2,6‑Xylidine (also called 2,6‑dimethylaniline) is a toxic industrial chemical used to make dyes, pesticides, and the anesthetic lidocaine. It matters because it can irritate skin and eyes and has caused cancer in animals; agencies consider it a possible human carcinogen [1][2].

Where It Comes From

Made as a chemical intermediate; releases can occur during manufacturing, processing, or waste handling [1][3].

How You Are Exposed

Mostly at work by breathing vapors or skin contact; the public may be exposed near industrial sites or from contaminated water/soil after spills [1][3].

Why It Matters

Short-term exposure can cause irritation, headaches, dizziness, and other nervous system or blood effects [3]. Long-term exposure caused nasal and liver tumors in animals [2][4].

Who Is at Risk

Workers in chemical, pharmaceutical, dye, or pesticide production; maintenance and cleanup crews; and people living near facilities using this chemical [1][3].

How to Lower Your Exposure

At work, use closed systems, local exhaust, gloves and protective clothing, and follow monitoring and hygiene practices; a properly fitted respirator may be needed [3]. In communities, support spill prevention, heed advisories, and use certified water filters if contamination is reported [1].

References

  1. [1]U.S. Environmental Protection Agency (EPA), Integrated Risk Information System (IRIS): 2,6-Xylidine (CASRN 87-62-7).
  2. [2]International Agency for Research on Cancer (IARC), Monographs: 2,6-Dimethylaniline (2,6-xylidine), Group 2B.
  3. [3]CDC/NIOSH, Pocket Guide to Chemical Hazards: 2,6-Xylidine.
  4. [4]National Toxicology Program (NTP), Toxicology and Carcinogenesis Studies of 2,6-Xylidine Hydrochloride in Rats and Mice.

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