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CAS 576-26-1

2,6-Dimethylphenol

2,6-Dimethylphenol (also called 2,6-xylenol) is an industrial chemical mainly used to make engineering plastics and other products. It is a toxic phenolic compound that can irritate skin, eyes, and lungs and is harmful to aquatic life [1][3].

Where It Comes From

Manufactured for use in resins (e.g., polyphenylene oxide), additives, and other intermediates; releases can occur during production, processing, and waste handling [1][2].

How You Are Exposed

Breathing workplace air during manufacturing/use, contact with contaminated surfaces or water near facilities, or accidental spills; general public exposure is usually low unless near sources [1][2][3].

Why It Matters

Can cause skin and eye irritation and harm if swallowed; high exposures have caused systemic effects in studies; very toxic to aquatic organisms. Major agencies have not classified it as a human carcinogen [2][3][4][5].

Who Is at Risk

Workers in plastics/resin manufacturing and people living near industrial plants or contaminated sites [1][2].

How to Lower Your Exposure

Use workplace controls (ventilation, protective gear), wash after handling, avoid contact with spills, follow local air/water advisories, and dispose/store chemicals per guidelines [1][2][3].

References

  1. [1]U.S. EPA CompTox Chemicals Dashboard: 2,6-Dimethylphenol (CASRN 576-26-1).
  2. [2]OECD SIDS Initial Assessment Report: 2,6-Xylenol (2,6-Dimethylphenol).
  3. [3]ECHA Brief Profile: 2,6-dimethylphenol.
  4. [4]IARC Monographs — Agents Classified by the IARC Monographs.
  5. [5]NTP Report on Carcinogens — Substance Profiles and Listings.

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