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CAS 1320-18-9

2,4-D propylene glycol butyl ether ester (2,4-D 2-butoxymethylethyl ester)

This herbicide ingredient is an ester form of 2,4-D used to control broadleaf weeds on farms, forests, and lawns. It breaks down to 2,4-D; exposure can irritate eyes/skin and raises concerns about long‑term health effects [1][3].

Where It Comes From

Agricultural and lawn sprays; ester formulations can be more volatile and drift, then hydrolyze to 2,4-D in soil and water [1].

How You Are Exposed

Breathing spray mist or vapors during/near applications, skin contact with treated plants/soil, accidental ingestion, or drinking contaminated well water [1][2].

Why It Matters

Short-term effects include eye/skin irritation, nausea, dizziness; high exposures may affect muscles, kidneys, and liver [1][4]. IARC classifies 2,4-D as possibly carcinogenic (Group 2B), while EPA finds it unlikely to be carcinogenic [3][5].

Who Is at Risk

Pesticide applicators and farmworkers; people living near treated fields; children and pets on recently treated lawns; private-well users in farming areas [1][2].

How to Lower Your Exposure

Follow label directions and wear protective gear; avoid spraying in heat/wind; keep people/pets off treated areas until dry/reentry time; protect and test wells; use certified filters (activated carbon or reverse osmosis). EPA’s drinking water limit for 2,4-D is 70 µg/L [1][2][6].

References

  1. [1]ATSDR. Toxicological Profile for 2,4-D (2,4-Dichlorophenoxyacetic Acid). 2020.
  2. [2]EPA. National Primary Drinking Water Regulations: 2,4-D (MCL 0.07 mg/L).
  3. [3]IARC Monographs Vol. 113. 2,4-Dichlorophenoxyacetic acid (2,4-D). Group 2B.
  4. [4]CDC/NIOSH Pocket Guide to Chemical Hazards: 2,4-D.
  5. [5]EPA. 2,4-D Registration Review Decision. 2020.
  6. [6]EPA Drinking Water Treatability Database: 2,4-D (GAC/RO).

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