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CAS 53404-37-8

2,4-D 2-ethyl-4-methylpentyl ester

This chemical is a weed-killer (an ester form of the herbicide 2,4-D) used on farms, lawns, and roadsides [1][2]. It breaks down to 2,4-D acid in the environment and body; exposure can irritate skin/eyes and, at high doses, affect nerves and muscles [1].

Where It Comes From

Herbicide products for crops, turf, forestry, and rights‑of‑way; it degrades to 2,4‑D acid after use [1][2].

How You Are Exposed

Breathing spray during/after application; skin contact when mixing/applying or touching treated plants/soil; swallowing residues in food or private well water near treated areas [1][2][4].

Why It Matters

Short‑term effects include eye/skin irritation, nausea/vomiting, dizziness; very high exposures can cause muscle weakness and nerve effects [1]. Cancer: IARC rates 2,4‑D as possibly carcinogenic (Group 2B) [3]; EPA finds 2,4‑D not likely carcinogenic at typical exposures [2].

Who Is at Risk

Applicators and farmworkers; families near treated fields; children and pets on recently treated lawns; people using private wells in agricultural areas [1][2][4].

How to Lower Your Exposure

Follow label directions; keep people/pets away until sprays dry; prevent drift and wear PPE when applying; wash hands and produce; remove shoes after outdoor work; test private wells if near frequent applications [1][2][4].

References

  1. [1]ATSDR. ToxFAQs for 2,4-D (2,4-Dichlorophenoxyacetic Acid). https://wwwn.cdc.gov/TSP/ToxFAQs/ToxFAQsDetails.aspx?faqid=245&toxid=44
  2. [2]U.S. EPA. 2,4-D – Ingredients Used in Pesticide Products. https://www.epa.gov/ingredients-used-pesticide-products/24-d-ingredients-used-pesticide-products
  3. [3]IARC Monographs, Volume 113: DDT, Lindane, and 2,4-D (2018). https://publications.iarc.fr/Book-And-Report-Series/Iarc-Monographs/DDT-Lindane-And-2-4-D-2018
  4. [4]CDC. Biomonitoring Summary: 2,4-D. https://www.cdc.gov/biomonitoring/24D_BiomonitoringSummary.html

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