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CAS 7012375

2,4,4-Trichlorobiphenyl (PCB-28)

VOCHAP

PCB-28 is one of the polychlorinated biphenyls (PCBs), man-made chemicals once used in electrical equipment and some building materials. It is a toxic, persistent pollutant that can build up in people and wildlife [1][2].

Where It Comes From

Legacy Aroclor PCBs in old transformers/capacitors, caulk and paints; leaks or improper disposal; releases from contaminated sites; and volatilization to indoor air from older building materials [1][2].

How You Are Exposed

Mainly by eating contaminated fish/seafood, meat, and dairy; also by breathing indoor/outdoor air and dust near older buildings or industrial areas, and contact with polluted soil or sediments [1][2].

Why It Matters

PCBs can harm the immune, thyroid, and reproductive systems and may affect children’s brain development; PCBs are carcinogenic to humans [1][3][4].

Who Is at Risk

Pregnant people, infants/children, frequent consumers of locally caught fish, residents of older buildings with PCB caulk/ballasts, and demolition/remediation or electrical workers [1][2].

How to Lower Your Exposure

Follow local fish advisories; choose lean cuts, trim fat, and broil/brush off drippings; ventilate and HEPA-vacuum dust; avoid disturbing old caulk/ballasts—use certified abatement; wash hands and damp-wipe surfaces [1][2].

References

  1. [1]ATSDR. Toxicological Profile for Polychlorinated Biphenyls (PCBs). U.S. DHHS, 2000 (update 2020).
  2. [2]U.S. EPA. Learn about Polychlorinated Biphenyls (PCBs) and PCBs in Building Materials.
  3. [3]IARC Monographs, Volume 107. Polychlorinated biphenyls. IARC, 2016 (Group 1).
  4. [4]NTP. Report on Carcinogens, 15th Ed. Polychlorinated Biphenyls, 2021.

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