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CAS 128903-21-9

2,2-Dichloro-1,1,1,3,3-pentafluoropropane (HCFC-225aa)

HCFC-225aa is a hydrochlorofluorocarbon solvent once used to clean electronics and metal parts. It depletes the ozone layer and contributes to climate change, so its production and use are being phased out or restricted. [1][2]

Where It Comes From

Industrial HCFC production; legacy stocks in precision-cleaning fluids and some aerosols; residues in older or imported equipment. [1][2][4]

How You Are Exposed

Breathing vapors during cleaning/degreasing at work, accidental releases from stored products, or use in enclosed, poorly ventilated areas. [2][3]

Why It Matters

Harms stratospheric ozone and has greenhouse warming potential; high vapor levels can cause headache, dizziness, and irritation. [1][2][3]

Who Is at Risk

Workers in electronics/metal cleaning and maintenance, people working in small or poorly ventilated spaces, and waste handlers managing old stocks. [2][3]

How to Lower Your Exposure

Choose EPA SNAP-listed alternatives; ensure good local exhaust ventilation; follow PPE and safety data sheets; avoid buying/using products labeled HCFC‑225/AK‑225; dispose of legacy materials through approved hazardous-waste programs. [1][2]

References

  1. [1]U.S. EPA. Phaseout of HCFCs (Class II Ozone‑Depleting Substances) – Ozone Layer Protection.
  2. [2]U.S. EPA. Significant New Alternatives Policy (SNAP) Program – Solvent substitutes and listings for HCFC‑225.
  3. [3]CDC/NIOSH. Organic Solvents – Occupational Safety and Health Topic.
  4. [4]U.S. EPA. CompTox Chemicals Dashboard: 2,2-Dichloro-1,1,1,3,3-pentafluoropropane (CASRN 128903‑21‑9).

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