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CAS 3296-90-0

2,2-Bis(bromomethyl)-1,3-propanediol

2,2-Bis(bromomethyl)-1,3-propanediol (also called dibromoneopentyl glycol, DBNPG) is a brominated flame‑retardant building block used to make certain plastics and resins. It is toxic; animal studies found it can cause cancer, and it can irritate and sensitize skin [1][2].

Where It Comes From

Manufacturing and use of flame‑retardant resins, coatings, and plastics; small amounts may be present as unreacted ingredient in finished products or released during processing and disposal [2].

How You Are Exposed

Mainly at work through skin contact or breathing dust/fumes during production, mixing, molding, cutting, or sanding treated materials; the general public may encounter low levels in dust near use or manufacturing sites [2].

Why It Matters

Caused tumors in multiple organs in rats and mice; human cancer risk is uncertain but of concern. Also causes skin/eye irritation and allergic skin reactions [1][2].

Who Is at Risk

Workers in plastics/resins, composite fabrication, and recycling; maintenance staff cutting or sanding FR panels; people living near production or waste sites [1][2].

How to Lower Your Exposure

At work, use closed systems, local exhaust, and wear chemical‑resistant gloves, eye/face protection, and protective clothing; follow your SDS. At home, avoid creating dust from treated materials, wet‑wipe and HEPA‑vacuum, and choose products labeled flame‑retardant‑free when feasible [2].

References

  1. [1]National Toxicology Program (NTP). Toxicology and Carcinogenesis Studies of 2,2‑Bis(bromomethyl)‑1,3‑propanediol (CASRN 3296‑90‑0).
  2. [2]U.S. EPA CompTox Chemicals Dashboard. 2,2‑Bis(bromomethyl)‑1,3‑propanediol (CASRN 3296‑90‑0).

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