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CAS 2422-79-9

12-Methylbenz(a)Anthracene

12-Methylbenz(a)anthracene (12-MBA) is a polycyclic aromatic hydrocarbon (PAH) formed when fuels and other materials burn; it’s mainly used in research. PAHs matter because some can damage DNA and raise cancer risk over time.[1][2]

Where It Comes From

By-products of burning (vehicle exhaust, wood smoke, coal tar, tobacco smoke); found in soot and tar alongside other PAHs.[1]

How You Are Exposed

Breathing smoky or traffic-related air; skin contact with soot, used motor oil, or coal‑tar–based products; eating heavily charred/grilled foods.[1]

Why It Matters

Several PAHs (e.g., benzo[a]pyrene) are known carcinogens, and benz[a]anthracene is possibly carcinogenic to humans; related methylated PAHs cause tumors in animals.[2]

Who Is at Risk

Smokers; people near heavy traffic or wildfires; workers handling coal tar, asphalt, or diesel exhaust (roofers, pavers, foundry workers).[1]

How to Lower Your Exposure

Avoid or ventilate smoke; keep indoor air clean; limit charring when cooking; wash off soot promptly; use protective gear and controls at work.[1]

References

  1. [1]ATSDR. Toxicological Profile for Polycyclic Aromatic Hydrocarbons (PAHs). Agency for Toxic Substances and Disease Registry. https://www.atsdr.cdc.gov/toxprofiles/tp69.pdf
  2. [2]IARC Monographs, Volume 92 (2010): Some Non-heterocyclic Polycyclic Aromatic Hydrocarbons and Some Related Exposures. International Agency for Research on Cancer. https://publications.iarc.fr/119

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