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CAS 31506-32-8

1-Octanesulfonamide, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluoro-N-methyl-

This PFAS chemical, also called N-methyl perfluorooctanesulfonamide (N-MeFOSA), is a man-made ingredient once used in stain- and water-repellent treatments and industrial coatings. It persists and can transform into PFOS, a toxic PFAS that builds up in people and the environment [1][3].

Where It Comes From

Past production and use in surface protectors, paper/packaging, and specialty coatings; ongoing release from legacy products and industrial sites [3].

How You Are Exposed

Drinking water, food, and house dust contaminated with PFAS; contact with treated textiles and papers; workplace air/skin contact in fluorochemical manufacturing or firefighting foam use [1][2].

Why It Matters

PFAS like PFOS are linked to immune effects, higher cholesterol, liver and thyroid changes, and developmental effects; N-MeFOSA can add to PFOS body burden [1][2][3].

Who Is at Risk

People near fluorochemical plants, airports, or fire-training areas; workers handling PFAS; pregnant people, infants, and those using private wells in affected areas [1][2][4].

How to Lower Your Exposure

Use certified filters (reverse osmosis or activated carbon with PFAS claims), check local water advisories, wet-dust/HEPA vacuum, limit use of stain-resistant treatments, follow fish advisories, and use workplace PPE and hygiene [2][4].

References

  1. [1]ATSDR. Toxicological Profile for Perfluoroalkyls (PFAS). 2021.
  2. [2]U.S. EPA. Our Current Understanding of the Human Health and Environmental Risks of PFAS. 2023.
  3. [3]U.S. EPA. Technical Fact Sheet – PFOS and PFOA (includes PFAS precursors). 2017.
  4. [4]CDC/ATSDR. PFAS and Your Health – Exposure, Health Effects, and Reducing Exposure. 2022.

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