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CAS 764-41-0

1,4-Dichloro-2-butene

1,4-Dichloro-2-butene is a chlorinated industrial chemical mainly used to make other chemicals. It is toxic; short-term exposure can irritate the eyes, skin, and lungs, and higher exposures can harm organs [1][2].

Where It Comes From

Made and used in chemical manufacturing (e.g., as an intermediate); releases may occur from plants or spills during transport [2].

How You Are Exposed

Mostly by breathing workplace air; also possible through skin contact or from contaminated air, soil, or water near industrial sites. Consumer exposure is unlikely [1][2].

Why It Matters

Can cause irritation, coughing, headache, and dizziness. High exposures may affect the liver and kidneys. Human data are limited; health risks are better documented in workplace and lab studies [1][2].

Who Is at Risk

Workers who make, use, or handle it; maintenance and emergency responders; people living near production sites; individuals with asthma or liver/kidney disease; pregnant workers [1][2].

How to Lower Your Exposure

At work, use closed systems, ventilation, monitoring, and appropriate PPE (gloves, goggles, respirators as needed). In communities, follow spill advisories and consider testing well water if near industrial facilities [1][2].

References

  1. [1]CDC/NIOSH Pocket Guide to Chemical Hazards: 2-Butene, 1,4-dichloro (CAS 764-41-0).
  2. [2]U.S. EPA CompTox Chemicals Dashboard: 1,4-Dichloro-2-butene (CASRN 764-41-0).

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