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CAS 136013-79-1

1,3-Dichloro-1,1,2,3,3-pentafluoropropane (HCFC-225ea)

HCFC-225ea is a man-made cleaning solvent used in precision electronics and aerospace. At high levels it can irritate the lungs and affect the nervous system, and it harms the ozone layer, so its use is tightly controlled and being phased out [1][2][3].

Where It Comes From

Specialty degreasing/defluxing and precision-cleaning processes; legacy stocks or older aerosol products [1][2].

How You Are Exposed

Breathing vapors during use at work, skin contact with liquid, spills, or using aerosol/parts-cleaning products in poorly ventilated spaces [1][3].

Why It Matters

Short-term exposure can cause headache, dizziness, drowsiness, and eye/throat irritation; very high levels may affect heart rhythm and cause loss of consciousness. It also depletes ozone and contributes to climate change [1][2][3].

Who Is at Risk

Workers in electronics, aerospace, and precision-cleaning; people with heart disease; anyone working in enclosed or poorly ventilated areas; pregnant workers should take extra caution [1][3].

How to Lower Your Exposure

Use safer alternatives where possible; keep processes closed and ventilated; follow EPA rules and Safety Data Sheets; wear appropriate gloves and eye protection; avoid spraying in small rooms; store and dispose legally [1][2][3].

References

  1. [1]U.S. EPA SNAP: Substitutes in Solvent Cleaning. https://www.epa.gov/snap/substitutes-solvent-cleaning
  2. [2]U.S. EPA: Phaseout of Hydrochlorofluorocarbons (HCFCs). https://www.epa.gov/ods-phaseout/phaseout-hydrochlorofluorocarbons-hcfcs
  3. [3]CDC/NIOSH: Organic Solvents – Workplace Safety and Health Topic. https://www.cdc.gov/niosh/topics/organsolv/

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