Where It Comes From
Made and used as a precision-cleaning and vapor-degreasing solvent; released to air during use, storage, and equipment leaks. [2][3]
How You Are Exposed
Mostly by breathing vapors during cleaning or spraying; possible skin contact with the cold liquid. People near facilities that use it may have air exposure. [1][3]
Why It Matters
Short-term exposure can cause dizziness, headache, and drowsiness; very high levels can lead to unconsciousness. When heated, it can break down into hydrogen fluoride and hydrogen chloride. Environmentally, it depletes ozone and is regulated/being phased out. [1][2]
Who Is at Risk
Workers in electronics/metal cleaning, maintenance, or aerosol filling; people in poorly ventilated spaces where it’s used. [1][3]
How to Lower Your Exposure
Prefer non‑ozone‑depleting alternatives approved by EPA SNAP; use strong ventilation/local exhaust; avoid indoor spraying; wear suitable gloves/eye protection; follow product/SDS directions and local disposal rules. [1][2][3]
References
- [1]WHO/ILO/UNEP IPCS. International Chemical Safety Card (ICSC): 1,3‑Dichloro‑1,1,2,2,3‑pentafluoropropane (HCFC‑225cb).
- [2]U.S. EPA. Phaseout of Hydrochlorofluorocarbons (HCFCs) under the Clean Air Act.
- [3]U.S. EPA SNAP Program. Substitutes in Solvent Cleaning (including HCFC‑225ca/cb) and related fact sheets.