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CAS 110-71-4

1,2-Dimethoxyethane

1,2‑Dimethoxyethane (monoglyme) is a flammable industrial solvent used in electronics, lithium batteries, and labs. It can irritate eyes and lungs; repeated exposure raises concerns about blood and reproductive effects. [1][2][3]

Where It Comes From

Made for use as a solvent and electrolyte co‑solvent in electronics, lithium‑battery manufacturing, adhesives/coatings, and chemical synthesis; it can be released during production, use, or spills. [1][2]

How You Are Exposed

Breathing vapors at work or during hobby use; skin contact with liquid; less often from indoor air after use or from air/water near facilities or spills. [1][3]

Why It Matters

Short‑term: headache, dizziness, nausea, and irritation. Longer‑term: EPA cites concerns for fertility and developmental effects in animals for glymes; some glycol ethers affect blood and organs. [1][2][3]

Who Is at Risk

Workers in labs, electronics/battery manufacturing or repair, painting/solvent use; pregnant people or those trying to conceive. [1][2]

How to Lower Your Exposure

Choose safer alternatives; use ventilation or fume hoods; avoid skin contact—wear chemical‑resistant gloves and eye protection; keep from flames; follow SDS and workplace controls; store sealed, dispose properly. [1][2]

References

  1. [1]CDC/NIOSH. NIOSH Pocket Guide to Chemical Hazards: Ethylene glycol dimethyl ether (Monoglyme), CAS 110-71-4.
  2. [2]U.S. EPA. Significant New Use Rules; Glymes. Federal Register, 80 FR 62470 (Oct 16, 2015).
  3. [3]ATSDR. ToxFAQs for Glycol Ethers. Agency for Toxic Substances and Disease Registry.

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