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CAS 0107-06-02

1,2-DICHLOROETHANE

Organic Chemicals, except for PFASCarcinogen

1,2-Dichloroethane (also called ethylene dichloride) is a colorless liquid used mostly to make vinyl chloride for PVC plastic. It is toxic; breathing or drinking it can harm the nervous system, liver, and kidneys and can increase cancer risk [1][2][3][4].

Where It Comes From

Chemical manufacturing and solvent uses; releases and spills from plants, storage tanks, and hazardous waste sites can contaminate air and groundwater [1][5].

How You Are Exposed

Breathing outdoor/indoor air near facilities or from some solvent products; drinking contaminated private well water; workplace exposure; skin contact with the liquid [1][2].

Why It Matters

Short-term exposure can cause dizziness, headache, and nausea; very high levels can be life‑threatening. Long-term exposure can damage the liver and kidneys and raise cancer risk [1][2][3][4].

Who Is at Risk

Workers in PVC/solvent production, people living near industrial sites or landfills, private-well users in affected areas, and people with liver or kidney disease [1][2].

How to Lower Your Exposure

Check local advisories; test private wells; use certified activated carbon or aeration treatment for VOCs; ventilate when using solvent products; follow workplace protections and dispose of chemicals properly [1][5].

References

  1. [1]ATSDR. ToxFAQs for 1,2-Dichloroethane (Ethylene dichloride). Agency for Toxic Substances and Disease Registry. https://www.atsdr.cdc.gov/toxfaqs/tfacts38.html
  2. [2]U.S. EPA. Integrated Risk Information System (IRIS): 1,2-Dichloroethane (CASRN 107-06-2).
  3. [3]IARC. IARC Monographs: 1,2-Dichloroethane (Group 2B – possibly carcinogenic to humans).
  4. [4]NTP. Report on Carcinogens, 15th Ed.: 1,2-Dichloroethane (reasonably anticipated to be a human carcinogen).
  5. [5]U.S. EPA. Technical Fact Sheet – 1,2-Dichloroethane (EDC). https://www.epa.gov/fedfac/technical-fact-sheet-12-dichloroethane-edc

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