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PFAS Exposure Linked to Autoimmunity in Humans and Animals

"Exposure to per- and polyfluoroalkyl substances (PFAS) and development of autoimmunity in humans and animals: a scoping review." — Archives of toxicology, 2026

April 24, 2026by AI Curated

PFAS Exposure Linked to Autoimmunity in Humans and Animals

What they found

A review of 51 studies found that PFAS exposure is associated with the development of autoimmunity, with 33 studies linking higher PFAS levels to increased risk.

What they studied

This scoping review mapped available evidence on PFAS exposure and autoimmunity in humans and animals, assessing associations with autoimmune diseases and autoantibodies.

Takeaways

The review highlights a need for further research to better understand the link between PFAS and individual autoimmune outcomes.

About this paper

This scoping review included 51 studies from various databases, identifying potential associations between PFAS exposure and autoimmunity. Most studies were cross-sectional, which limits the ability to infer direct causation.

pfasautoimmunityimmune systemtoxicologyscoping reviewhealthchemicalscurated

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